CBD and epilepsy

CBD would seem to have opened a new path in the treatment of epilepsy. A very interesting therapeutic property of the so- called cannabidiol is its anticonvulsive and antiepileptic effect. The property opened new perspectives for some types of epilepsy resistances than most of the antiepileptic drugs in use today.

Epilepsy is a neurological disease that occurs following an alteration in neuronal activity in some areas of the brain. The direct effects are seizures, which can be of many types, depending on the degree of epilepsy suffered.

The disease itself causes cognitive and psychological problems, with side effects, which can also be very serious.

The use of CBD for the treatment of epilepsy has resulted in interesting effects starting from the re-modulation that cannabinoid intake causes on neuronal activity, attenuating the hyperexcitability that the epileptic patient presents. In addition, cbd tends to reduce oxidative stress responsible for brain damage in epilepsy due to its anti-neuroinflammatory action.

In cases of childhood epilepsy in which convulsions cannot be contained, CBD can be an effective complement to control them. In this sense Epidiolex, a strawberry-flavored syrup rich in highly purified CBD has given the patients very encouraging results.

In Dravet syndrome, a type of infantile epilepsy of genetic origin, resistant to antiepileptic drugs, the symptoms begin in the first year of life, with chronic convulsions and with a mortality rate during crisis moments of 14%. For this syndrome, there is no specific drug approved by the World Health Organization and for this reason, for treatment, many patients use generic antiepileptic drugs in combination with a ketogenic diet. Also, in this case, it has been shown that the use of CBD for epilepsy can be an excellent aid.

Despite numerous scientific studies on the antiepileptic properties of cannabinoids, there are still some concerns with being able to definitively determine the relationship between CBD and therapeutic effects on epilepsy. However, the numbers say that the epileptic subjects who take cannabidiol have found extremely positive results. These are preclinical studies, of course, but they show that CBD can be considered a serious antiepileptic therapeutic alternative, always bearing in mind that it cannot replace pharmaceutical therapy — it can, however, be used in combination with the same. Its anticonvulsant and neuroprotective effect is very useful for people suffering from epilepsy, as it protects them from the progression of the cognitive and psychomotor delays typical of the disease.

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